Wildfires

peterhutch asked:


Bloom’s syndrome is characterized by severe prenatal and postnatal growth retardation and a sun-sensitive erythematous skin lesion that occurs most commonly on the face. Recurrent infections (otitis media and pneumonia), chronic pulmonary disease, and diabetes mellitus are common. Many have learning disabilities. Males are infertile; females enter menopause prematurely.

Characteristics commonly seen in Bloom’s syndrome are small stature (average adult male height of 151 cm, average adult female height of 144 cm), skin photosensitivity, and a high-pitched voice. A typical ****** appearance has also been described consisting of a narrow face with prominent nose and prominent ears. Immunodeficiency has been seen, which results in an increased number of respiratory tract and ear infections.

Mutations in the Bloom syndrome , which is a member of the DNA helicas family. DNA helicases are enzymes that unwind the two spiral strands of a DNA molecule so that they can be copied. When a cell prepares to divide to form two cells, the chromosomes are duplicated so that each new cell will get a complete set of chromosomes; this replication process involves unwinding the DNA so that it can be copied. The BLM protein is important in maintaining the stability of the DNA during this process.

This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

Causes

Bloom syndrome is apparent from birth with affected newborns being unusually small. Most parents seek medical help when the infant does not grow normally. Over 50% of children are significantly underdeveloped in physical stature until age 8 years, and most fail to reach 1.5 metres (5 feet) in adulthood.

Bloom’s Syndrome is inherited in an autosomal recessive pattern, which means two copies of the gene must be altered for a person to be affected by the disorder. The gene for Bloom’s syndrome is located on chromosome 15; one particular mutation in the gene has been identified as the cause of Bloom’s syndrome in the vast majority of Ashkenazi Jews.

Diagnosis

The diagnosis of Bloom’s syndrome can be confirmed or ruled out by a laboratory test known as a chromosome study, as blood and skin cells show a characteristic pattern of chromosome breakage and rearrangement. Recently, the gene for Bloom’s syndrome was isolated. The gene is located on chromosome 15, and one particular mutation in the gene has been identified as the cause of Bloom’s syndrome in the vast majority of Ashkenazi Jews. Because of these recent findings, both carrier testing and prenatal diagnosis for Bloom’s syndrome are now available.

Treatment

There is no treatment for the underlying cause of Bloom’s syndrome, and therefore medical intervention is primarily preventative. Adults with Bloom’s syndrome should be more attentive and cautious than others in their surveillance for cancer. It is recommended that people afflicted by this disease maintain close contact with a physician familiar with Bloom’s.



JEFFREY

Juliet Cohen asked:


Burning mouth syndrome (BMS) is a condition that causes pain in the mouth, lips or tongue without any clear reason. There are often no visible signs of irritation. The cause of the syndrome may be caused by the onset of menopause to vitamin deficiencies. Both men and women can get BMS. About 5% of the population, usually people over the age of 60 are affected with this condition. Personality and mood changes (especially anxiety and depression) have been consistently demonstrated in patients with burning mouth syndrome and have been used to suggest that the disorder is a psychogenic problem.

Burning mouth syndrome has not been linked to any specific medical condition, associations with a wide variety of concurrent health conditions and chronic pain conditions, involved headaches. Using blink reflex and thermal quantitative sensory tests have demonstrated signs of neuropathy in most people with burning mouth syndrome. Hormonal changes are still considered to be important factors in burning mouth syndrome. Other possible causes of BMS include nutritional deficiencies, allergies, certain medications, certain medical conditions, hormonal changes during menopause and dry mouth.

Treatment of burning mouth syndrome is highly individualized and depends on your particular signs and symptoms and on the underlying cause or causes. Treatment triggers improvement in symptoms for most people with burning mouth syndrome. Use of low dosages of clonazepam (Klonopin), chlordiazepoxide (Librium)13 and tricyclic antidepressants. Capsaicin (hot pepper) mouth rinses may also help some people with BMS. Thioctic acid may be a treatment for burning mouth syndrome. Burning mouth syndrome (BMS): double blind controlled study of alpha-lipoic acid (thioctic acid) therapy.

Avoiding foods that contain allergens that may irritate the tissues of your mouth may help. Tongue thrusting and teeth grinding (bruxism) can be helped with mouth guards, medications and relaxation techniques. There are many other tips is helpful this condition. Brush your teeth/dentures with baking soda and water. Avoid alcohol and tobacco products. Avoid irritating substances like hot, spicy foods; mouthwashes that contain alcohol; and products high in acid, like citrus fruits and juices.



JOHNNIE

David Cowley asked:


Virtually everyone today is interested in weight control, and this means both men and women.  Obesity rates are skyrocketing everywhere and even children are becoming affected.  But while it’s easy to gain weight, losing it and controlling it are very difficult for most.  Without taking harsh medicines or undergoing dangerous surgery, you may want to consider trying a natural weight control treatment first.

You can loose weight one of two ways.  You can decrease the amount of calories you intake below the amount of calories you use.  You can increase the amount of calories you use above your caloric intake.  The best and most effective technique is to do both.  Increase your activity level and reduce the amount of calories you take in to your body.  The less calories you intake and the more calories you use determine how fast you will lose weight.  Where you get your calories from may or may not be important and information concerning where you get your calories, from fat or carbohydrates for example, seems to change with every new study published.

Remember that there is probably no product on the market that will accomplish weight control without you having to make some changes in your eating habits and physical activity level either.  You just can’t stuff yourself with thousands of calories every single day, never get off the couch, and then take a pill that will keep you healthy and slim.  All natural weight control products require the user to do his or her part with diet and exercise.  Expecting anything else is a surefire recipe for disaster.

Controlling your calorie intake is a big part of natural control for your weight but it is also important to pay attention to what you eat.  Many new diets are extolling the advantages of filling up on protein.  This is because protein helps to make a person feel full and has few calories for the amount of food you eat.  Sugar spikes your feelings of hunger and so encourages you to eat more.  By understanding how these foods break down in your system and how they affect your hunger pangs, you can better modify your diet for natural weight control.

There are some herbs and natural ingredients you can use to help with weight control.  These include chromium which helps to maintain your blood sugar levels.  When the blood sugar dips the body sends out a hunger signal, as eating helps to get that sugar level back to normal.  Green tea extract also helps to burn calories.  Very hot or spicy foods such as pepper and garlic help to shed excess water weight. 

Melatonin helps to regulate the body’s sleep cycle, and proper rest is important for the body to maintain metabolism and burn calories efficiently.  L-Carnitine is used to turn food into energy, especially fat.  Phenylalanie is an amino acid and acts directly on the appetite center of the brain to help suppress the cravings for food.  MetaboVite is the natural weight control supplement developed to raise the body’s metabolism.

All of these suggestions should also be used in conjunction with drinking plenty of fluids so that the body can flush fat and other toxins out of its system.  Proper digestion and good blood circulation is important for any diet system you try, so it’s imperative that you drink plenty of water.  Cider Vinegar is an excellent source of potassium, which is lost during exercise, and also is helpful in emulsifying fats.

Scientists and doctors are working on natural weight medications and treatment options all the time; perhaps one day they will invent that magic pill that will let us eat whatever we want in whatever quantities we want and still remain slim.  In the meantime it’s important to be proactive and take personal responsibility for our own weight control plan.

Always consult your doctor before using this information.

This Article is nutritional in nature and is not to be construed as medical advice.



KENDRICK